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Aging and Health: A Systems Biology Perspective

Objektkategorie:
Elektronische Ressource
Person/Institution:
Yashin, Anatoliy I.
Jazwinski, S. Michal
Verlag:
Karger
Veröffentlichungsort:
Erscheinungsort nicht ermittelbar
Entstehungszeit:
2014
Umfang, Illustration, Format:
1 Online-Ressource
Sprache:
Englisch
Bereitstellende Institution:
Forschungsbibliothek Gotha
GND Explorer
Abstract:
Aging is a major risk factor for chronic diseases, which in turn can provide information about the aging of a biological system. This publication serves as an introduction to systems biology and its application to biological aging. Key pathways and processes that impinge on aging are reviewed, and how they contribute to health and disease during aging is discussed. The evolution of this situation is analyzed, and the consequences for the study of genetic effects on aging are presented. Epigenetic programming of aging, as a continuation of development, creates an interface between the genome and the environment. New research into the gut microbiome describes how this interface may operate in practice with marked consequences for a variety of disorders. This analysis is bolstered by a view of the aging organism as a whole, with conclusions about the mechanisms underlying resilience of the organism to change, and is expanded with a discussion of circadian rhythms in aging
Objekttext:
English

Zugriff und Nutzungsmöglichkeiten

Universität Erfurt
Forschungsbibliothek Gotha
Schloss Friedenstein
Schlossplatz 1
99867 Gotha
+49 361 737-5540
bibliothek.gotha(at)uni-erfurt.de
Datensatz angelegt am:
2023-04-14
Zuletzt geändert am:
2023-03-01
In Portal übernommen am:
2023-04-14