A study on cholinergic signal transduction pathways involved in short term and long term memory formation in the rat hippocampus: Molecular and cellular alterations underlying memory impairments in animal models of neurodegeneration
Object category:
Elektronische Ressource
Person/Institution:
Publisher:
Firenze University Press
Place of publication:
Florence
Date:
2015
Extent, illustration, format:
1 Online-Ressource (136 p.)
Language:
Nicht zu entscheiden
Providing institution:
Additional information
Abstract:
Neurodegenerative processes alter neuronal and glial physiology and cause cognitive and mnemonic impairments. Aim of this PhD thesis is to investigate the involvement of the cholinergic system and the role of mTOR pathway in the mechanisms of memory encoding in the hippocampus and to study the pathophysiological processes at the base of the cognitive impairments in different experimental models of neurodegeneration: in particular normal brain aging, neuroinfiammation and chronic cerebral hypoperfusion. These mechanisms are studied focusing on the morpho-functional alterations in the neuron-astrocytemicroglia triad
Object text:
English
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Contact
Universität Erfurt
Forschungsbibliothek Gotha
Schloss Friedenstein
Schlossplatz 1
99867 Gotha
+49 361 737-5540
bibliothek.gotha(at)uni-erfurt.de
Forschungsbibliothek Gotha
Schloss Friedenstein
Schlossplatz 1
99867 Gotha
+49 361 737-5540
bibliothek.gotha(at)uni-erfurt.de
Administrative details
Created:
2023-04-13
Last changed:
2023-01-29
Added to portal:
2023-04-13
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