A Master Regulator of Oxidative Stress - The Transcription Factor Nrf2
Object category:
Elektronische Ressource
Person/Institution:
Publisher:
IntechOpen
Place of publication:
Erscheinungsort nicht ermittelbar
Date:
2016
Extent, illustration, format:
1 Online-Ressource (210 p.)
Language:
Englisch
Providing institution:
Additional information
Abstract:
Due to that at present, the majority of diseases are associated with alterations in oxidative stress and inflammatory processes, and in that Nrf-2 is a modulator of these processes; knowing how this transcriptional factor functions and is regulated opens a therapeutic window to diverse diseases. Therefore, the efforts of various investigation groups are centered on finding activators and/or inhibitors of Nrf-2 to prevent or control diverse diseases, for example, cancer, where it would be important to regulate Nrf-2 in order for it to activate apoptosis pathways in cancerogenous cells, or in neurodegenerative diseases where cell death is predominant, it would be important for Nrf-2 to activate antiapoptotic pathways
Object text:
English
Access and usage options
Contact
Universität Erfurt
Forschungsbibliothek Gotha
Schloss Friedenstein
Schlossplatz 1
99867 Gotha
+49 361 737-5540
bibliothek.gotha(at)uni-erfurt.de
Forschungsbibliothek Gotha
Schloss Friedenstein
Schlossplatz 1
99867 Gotha
+49 361 737-5540
bibliothek.gotha(at)uni-erfurt.de
Administrative details
Created:
2023-04-12
Last changed:
2021-11-26
Added to portal:
2023-04-12
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