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Acute Myelogenous Leukemia

Object category:
Elektronische Ressource
Person/Institution:
Karp, Judith E.
Publisher:
Humana Press
Place of publication:
Totowa, NJ
Date:
2007
Extent, illustration, format:
Online-Ressource v.: digital
Language:
Englisch
Abstract:
This is a timely compilation of new concepts in the molecular pathogenesis and molecular therapy of acute myelogenous leukemia (AML). The focus is on selected critical molecular determinants of AML pathogenesis and pathophysiology and the exploitation of these factors by diverse therapeutic agents and modalities. There is an emphasis throughout on the bidirectional flow of knowledge between the clinical and laboratory arenas.
Presents a compilation of various concepts in the molecular pathogenesis and molecular therapy of acute myelogenous leukemia (AML). This book focuses on selected critical molecular determinants of AML pathogenesis and pathophysiology and the exploitation of these factors by diverse therapeutic agents and modalities
Object text:
edited by Judith E. Karp
Includes bibliographical references and index
Electronic reproduction; Available via World Wide Web
Online-Ausg. 2007 Springer eBook Collection. Medicine Electronic reproduction; Available via World Wide Web |2007||||||||||
Contents:
Approaching the treatment of AML from a biological perspective : an overview / Farhad Ravandi and Francis GilesAberrant transcription factors in AML / Alan D. Friedman -- Myelodysplasia-related AML / Jane E. Parker -- Therapy-related AML / Lucy A. Godley and Michelle Le Beau -- The DNA damage response, DNA repair, and AML / David P. Steensma -- Altered apoptosis in AML : potential implications for pathogenesis and therapeutic response / Ruben A. Mesa and Scott H. Kaufmann -- Drug resistance transporters in AML / Douglas D. Ross -- Impact of cytogenetics on clinical outcome in AML / David Grimwade -- APL : a classic tale of bench to bedside / Olga Frankfurt ... [et al.] -- Emerging therapeutics for AML / Edward A. Sausville -- FLT3 : a prototype receptor tyrosine kinase target in AML / Mark Levis -- Farnesyl transferase inhibitors in the therapy of AML / Jeffrey E. Lancet -- Modulating gene expression as a therapeutic approach in the treatment of AML / Tamer Fandy, Hetty Carraway, and Steven D. Gore -- Differentiation therapy in AML / Tara L. Lin and William Matsui -- Stem cell transplantation for AML / Javier Bolaños-Meade and Richard J. Jones -- Tumor vaccines in leukemia / Ivan Borrello -- Treatment, outcomes, and challenges of newly diagnosed AML in children and adolescents / Robert J. Arceci -- AML in older adults / Richard M. Stone -- Dameshek smiles : molecular clues to the chronic myeloproliferative disorders unmasked / Jason Gotlib -- New designs for clinical trials / Elihu Estey.

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Forschungsbibliothek Gotha
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bibliothek.gotha(at)uni-erfurt.de
Created:
2023-04-14
Last changed:
2022-09-03
Added to portal:
2023-04-14